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Mutants Y530A-SntA, Y633A-SntA, and Y530A+Y633A-SntA were obtained and kinetically characterized. For orientation towards the catalytic site, one tyrosine is enough, although this may depend on the substrate being attacked. On the other hand, both tyrosines are required for efficient binding of good SntA substrates.
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SNTA is listed in the World's most authoritative dictionary of abbreviations and acronyms. SNTA - What does SNTA stand for? The Free Dictionary.
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Mar 22, 2022 · SntA is overexpressed under iron starvation (Li et al., 2009), and it is a heme-binding protein that favors iron acquisition from infected host reservoirs, also inhibiting host antioxidant protein AOP2 (Wan et al., 2017). Moreover, SntA interferes with the action of complement (Deng et al., 2018).
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SntA can interact with the host antioxidant protein AOP2 and consequently inhibit its antioxidant activity. In the present study, SntA is identified as a cell wall …
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